Lola Bunny is a perfume saleswoman who perfects her own fragrance thanks to the introduction of a rare flower provided by her landlord, Speedy Gonzales, which, unfortunately, the military also wants. Lola meets misanthropic cab driver Bugs Bunny, who longs for anonymity, only to be thrust into the spotlight when he and Lola both end up on the FBI's most wanted list, hunted by federal agent Elmer Fudd. What neither Lola or Bugs know is that the flower in the perfume turns people and objects...

Takes place in London, as various jewel heists baffle Scotland Yard, and a beautiful singer named Red gets framed as the culprit. A situation of this magnitude calls for drastic action, and soon the legendary Sherlock Homes hits the beat, with Dr. Watson and Tom and Jerry in tow. But the case grows even more challenging when Tom and Jerry resort to their old crazy tricks and games with one another. Favorite supporting characters from the original Tom and Jerry series also turn up, including...